What is Collagenase?
Posted by Sara On Thu 28 Mar, 2019

  • Almost all commercial available collagenases are produced by the bacterium Clostridium histolyticum

  • C. histolyticum secretes two collagenases (class I & class II), neutral protease and clostripain

  • These four enzymes work together to dissociate the extracellular matrix (ECM). They are widely used for cell isolation from tissue

Collagenase - mediated tissue dissociation is a crucial step in cell isolation procedures influencing yield, viability and function of cells.
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